FDA OKs portable overdose antidote

Published 12:00 am Friday, April 4, 2014

Federal health regulators approved a drug overdose treatment device Thursday that experts say will provide a powerful, life-saving tool.

Similar to an EpiPen used to stop allergic reactions to bee stings, the easy-to-use injector will be prescribed for emergency use by the relatives or friends of people who have overdosed.

The handheld device, called Evzio, delivers a single dose of naloxone, a medication that reverses the effects of an overdose, and will be used on those who have stopped breathing or lost consciousness from an opioid drug overdose. Naloxone is the standard treatment in such circumstances, but until now, has been available mostly in hospitals and other medical settings, when it is often used too late to save the patient.

The decision to quickly approve the new treatment, which is expected to be available this summer, comes as deaths from opioids continue to mount, including an increase in those from heroin, which contributed to the death of actor Philip Seymour Hoffman in February. Federal health officials, facing criticism for failing to slow the rising death toll, are under pressure to act, experts say.

“This is a big deal and I hope gets wide attention,” said Dr. Carl Sullivan III, director of the addictions program at West Virginia University. “It’s pretty simple: Having these things in the hands of people around drug addicts just makes sense because you’re going to prevent unnecessary mortality.”

Some states have already taken steps to make naloxone more broadly available, though mostly through a patchwork of pilot programs.

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