FOXBOROUGH, Mass. — Ronnie Brown and the lowly Miami Dolphins ended the Patriots’ record regular-season winning streak at 21 and made New England’s defense look as shaky as its Tom Brady-less offense Sunday.

Brown scored a team record four touchdowns rushing and threw for another — with four of the scores coming on direct snaps to the running back — as Miami stunned New England 38-13.

The loss ended the Patriots’ NFL mark that began after a 21-0 loss to the Dolphins on Dec. 10, 2006, in which Brady was sacked four times. It also ended New England’s chance for a second straight unbeaten regular season.

The Dolphins, who lost their first 13 games last year and finished 1-15, won for just the second time in 22 games. It was the first victory for first-year coach Tony Sparano, and it was a stunner.

The Patriots kept getting fooled by the same trickery: six direct snaps resulting in four touchdowns after the Dolphins didn’t use the play in their other two games.

And New England didn’t have the injured Brady to lead a winning comeback as he’s done 28 times in the fourth quarter.

Brown gained 113 yards on 17 carries and the Dolphins outgained the Patriots 461 yards to 216.

Also on Sunday:

Bills 24

Raiders 23

ORCHARD PARK, N.Y. — Rian Lindell hit a 38-yard field goal as the clock ran out for Buffalo. Trent Edwards engineered three scoring drives in the final quarter, helping the Bills twice overcome 9-point deficits in the last 8 minutes. Edwards finished 24 of 39 for 279 yards and a touchdown.

Giants 26

Bengals 23

EAST RUTHERFORD, N.J. — The Giants (3-0) are off to their best start since 2000. John Carney kicked a 22-yard field goal with 8:39 left in the extra session. The play that set up the winning kick was a 31-yard pass from Eli Manning to Amani Toomer down the left sideline on a third-and-10 from the Bengals 38. It was difficult to tell whether Toomer got both feet in bounds. The Giants hustled to the line of scrimmage and handed the ball to Derrick Ward for a 3-yard run to the Bengals 4, precluding a video review.

Buccaneers 27

Bears 24

CHICAGO — Brian Griese set up Matt Bryant’s winning 21-yard field goal in overtime with a 38-yard pass to Antonio Bryant. After blowing a 14-point lead in a 20-17 loss at Carolina last week, the Bears (1-2) couldn’t protect a 24-14 advantage in the fourth quarter.

Vikings 20

Panthers 10

MINNEAPOLIS — Antoine Winfield’s sack of Jake Delhomme and subsequent 19-yard fumble return for a touchdown right before halftime spurred the Vikings, handing the Panthers (2-1) their first defeat. Replacing Tarvaris Jackson after a pair of woeful games by the offense, Gus Frerotte might have helped save the season for Minnesota (1-2) by completing 16 of 28 passes for 204 yards, with a touchdown to Visanthe Shiancoe.

Titans 31

Texans 12

NASHVILLE, Tenn. — LenDale White ran for two touchdowns, Kerry Collins threw for another and Tennessee rolled to improve to 3-0 for only the third time in franchise history. The Texans (0-2) scored only 12 points despite getting inside the Tennessee 14 six times.

Redskins 24

Cardinals 17

LANDOVER, Md. — Carlos Rogers returned a tipped interception to Arizona’s 15-yard line. Two plays later, Santana Moss took a receiver screen for a 17-yard touchdown that gave the Redskins the victory. Jason Campbell completed 23 of 31 passes for 193 yards with two touchdowns.

Falcons 38

Chiefs 14

ATLANTA — Michael Turner ran for three touchdowns and the Falcons scored the first 24 points, giving the Chiefs their 12th straight loss. Turner had scoring runs of 4, 1 and 2 yards, his first game with three touchdowns rushing, while leading the Falcons (2-1) with 104 yards on the ground.

Jaguars 23

Colts 21

INDIANAPOLIS — After wearing out the Indianapolis defense on the ground, Josh Scobee saved the game — and perhaps the season — by making a 51-yard field goal with 4 seconds left. It didn’t look like Jacksonville (1-2) would need Scobee’s boot after consuming more than 12 minutes on a marathon drive to open the fourth quarter capped by Scobee’s 21-yarder for a 20-14 lead with 2:33 left.

Broncos 34

Saints 32

DENVER — No gutsy two-point call this week. Just a gut-wrenching close call. Martin Gramatica’s 43-yard field goal try with 1:55 remaining was wide right, and the Broncos escaped. They improved to 3-0 for the first time in five years despite allowing Drew Brees to complete 39 of 48 passes for 421 yards and a touchdown, and Reggie Bush to pile up 178 all-purpose yards and two touchdowns.

Eagles 15

Steelers 6

PHILADELPHIA — Brian Westbrook limped off the field in the first half. Donovan McNabb missed part of the third quarter. With their best player sidelined and star quarterback hurting, the Eagles did it with defense. A swarming D had nine sacks, forced a safety and got three turnovers.

49ers 31

Lions 13

SAN FRANCISCO — Frank Gore rushed for 130 yards and a touchdown, and Mike Martz’s new offense methodically chewed up his former team’s defense. Isaac Bruce and Delanie Walker caught touchdown passes from J.T. O’Sullivan, and kick returner Allen Rossum scored a 1-yard touchdown rushing on fourth down near the goal line to all but clinch the win for San Francisco.

Seahawks 37

Rams 13

SEATTLE — Julius Jones ran for 140 yards on 22 carries and T.J. Duckett had his first two-touchdown rushing day in four years as the Seahawks sidestepped six injuries at wide receiver and rolled over the malfunctioning Rams.

Ravens 28

Browns 10

BALTIMORE — Baltimore turned two of Derek Anderson’s interceptions into a pair of touchdowns during a 50-second span of the third quarter. Ed Reed returned one of the interceptions 32 yards for a score, and Le’Ron McClain scored his first two NFL touchdowns on a pair of 1-yard runs.

Cowboys 27

Packers 16

GREEN BAY, Wis. — Dallas leaned on its defense and running game — then unleashed little-known wide receiver Miles Austin to put away Green Bay. Marion Barber ran for a career-high 142 yards and a touchdown, and rookie Felix Jones added a 60-yard touchdown run in the second quarter. Austin, a backup who plays mostly on special teams, sealed the win with a 52-yard touchdown reception in the fourth quarter. Tony Romo was 17-of-30 for 260 yards and Terrell Owens was held to two catches for 17 yards as Dallas (3-0) joined the reigning Super Bowl champion New York Giants as the NFC’s only undefeated teams.