PULLMAN, Wash. — Oregon running backs Jeremiah Johnson and LeGarrette Blount were faced with one of the worst rush defenses in the nation when they came to Washington State on Saturday.

The result was no content.

Blount rushed for 98 yards and three touchdowns, and Johnson added 89 yards and three touchdowns, as Oregon romped to a 63-14 win that embarrassed the woeful Cougars during their homecoming game.

Johnson likes to scamper and make tacklers miss, while Blount is more of a straight-ahead charger. The combination proved too much as Oregon (4-1, 2-0 Pac-10) gained 346 yards on the ground and 507 overall in crushing Washington State for the second straight year.

“We bring hard-nosed football and some teams can’t handle it,” said Johnson, who averaged 8.9 yards on 10 carries.

Washington State defensive back Xavier Hicks, who made 14 tackles as the Ducks surged through the defensive line all game, said the Cougars (1-4, 0-2) missed too many tackles.

“They put in fresh legs every down and just kept trying to pound it down,” Hicks said.

Jaison Williams caught two touchdown passes as Oregon rebounded from last weekend’s loss to Boise State that knocked the Ducks out of the Top 25. Quarterback Jeremiah Masoli completed nine of 16 passes for 161 yards.

The 63 points scored by Oregon was the most in the 86-game series, and the 49-point margin of victory is the largest ever in the series.

Washington State has been blown out by all four major college teams it has faced, beating only Portland State of the FCS last weekend. The Cougars managed only 271 yards as they continue to struggle under new coach Paul Wulff. Their rush defense ranks third from the bottom in major college football, yielding an average of 249 rushing yards per game

Freshman quarterback Marshall Lobbestael, making the first start of his career, completed 22 of 41 passes for 192 yards and two touchdowns, but was intercepted twice. He also suffered one of the Cougars’ two lost fumbles.

“Three turnovers is too much for my first start or my 10th start,” Lobbestael said. “There was no way they were that many points better than us.”

Earlier this season, the Cougars lost 66-3 to Cal for the worst margin of defeat in team history. But the Cougars are not giving up, defensive lineman Andy Mattingly said.

“We need to keep our heads up and come up tomorrow and get ready for UCLA,” he said.

The Ducks scored on their first three possessions to put the game away early.

On the opening possession, Lobbestael was stripped of the ball by Brandon Bair and Nick Reed recovered for the Ducks on WSU’s 28. Johnson ran it in from the 7 for a 7-0 lead.

“That gave them momentum,” Lobbestael said.

On the ensuing kickoff, WSU returner Chris Ivory fumbled and it was recovered on the 22 by Oregon’s Jairus Byrd. Masoli fired a pass to Williams in the end zone and Oregon had a 14-0 lead 3 minutes into the game.

Blount ran 13 yards up the middle for a touchdown on the Ducks’ third possession.

Washington State had an 82-yard drive that was kept alive by a pass interference call that nullified an Oregon interception near its own end zone. Lobbestael had a 9-yard touchdown pass to Jeshua Anderson to narrow Oregon’s lead to 21-7.

But Oregon replied with an 80-yard drive highlighted by Johnson’s 45-yard run that set up his 10-yard touchdown burst for a 28-7 lead. They went 78 yards on their next possession, with Blount going 3 yards up the middle for a 35-7 lead at halftime.

How good was Oregon’s offense? On the opening drive of the second half, the Ducks went for it on 4th-and-6 from the 33, with Masoli hitting Williams down the left sideline for a 42-7 lead.

Oregon coach Mike Bellotti was effusive in his praise for his team.

“I thought it was a total team victory,” involving offense, defense and special teams, he said.

Oregon, which won 53-7 last year, leads the series 41-38-7.